The first eight episodes aired were actually the last filmed. The final five episodes with the "new" uniforms were the first filmed before TNT halted production to completely redesign the show's set and costumes.

J. Michael Straczynski tried to remove his name from the writer credits. He registered the pseudonym "Eiben Scrood" with the WGA, but the WGA caved the pressure of WB and would not allow JMS to use a pseudonym.

Contains several similarities with the anime series Star Blazers. The biggest is the fact that both shows are about starships sent from Earth to retrieve the cure for a planetary disaster. Another is the "primary weapon" of the ships - a massively powerful one-shot cannon.

J. Michael Straczynski dedicated episode #1.7, "The Rules of the Game, airdate 7/21/1999, "In Memory of Mister Kitty, 198? to May 17, 1999, Now Chasing Star Mice"

Part of Gary Cole's costume was a class ring for "Earthforce Academy". He kept the ring and wore it in his next role, as Lumberg in Office Space.

Galen: Who are you?

Gideon: Captain Matthew Gideon.

Galen: What do you want?

Gideon: To find a cure for the Drakh plague before it wipes out all life on Earth.

Galen: Where are you going?

Gideon: Anywhere I have to.

Galen: Who do you serve, and who do you trust?  Who do you serve, and who do you trust?

Gideon: I don't know.

Galen: Then I will go with you.

Gideon: Why me? There are others just as qualified.

Senator McQuate: During your time captaining an Explorer-class vessel you've come across more new alien lifeforms than anyone else in the Fleet. There are half a dozen captains riding Explorer ships; the rest are either too old or too cautious. You're a dangerous man when you want to be, Captain, and right now we need a dangerous man.

Senator McQuate: You know, Captain, folks think there might have been life on Mars once. If they did exist, they left no sign. We'll never know who they were or what they did, what songs they sang, what stories they told. Mars is a dead world. I can't imagine that happening to the Earth in a few years. I can't imagine that happening at all.

Gideon: Just so we're clear: once we go, this is my command. I'll do whatever's necessary. If that means turning the entire galaxy upside down and shaking its pockets to see what falls out, that's what I'll do. I'm not subtle, I'm not pretty, and I'll piss off a helluva lot of people along the way, but I'll get the job done.

Galen: When you have reached the end of the road, then you can decide, whether to go to the left or to the right, to fire or to water. If you make those decisions before you have even set foot upon the road, it will take you no where... except to a bad end.

Elizabeth Lochley: Do you know what you are?

Gideon: Ruggedly handsome?

Elizabeth Lochley: A control freak!

Gideon: Can't I be both?

Galen: There is always hope. Only because it's the one thing that no one has figured out how to kill yet.